Statins: is it safe and effective to use generic "equivalents"?

نویسندگان

  • Cynthia A Jackevicius
  • Jack V Tu
  • Harlan M Krumholz
چکیده

Editorial Statins: Is it Safe and Effective to Use Generic “Equivalents”? Cynthia A. Jackevicius, BScPhm, PharmD, MSc, Jack V. Tu, MD, PhD, and Harlan M. Krumholz, MD, SM a Department of Pharmacy Practice and Administration, College of Pharmacy, Western University of Health Sciences, Pomona, California, USA b Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada c Institute of Health Policy, Management and Evaluation, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada d Veterans Affairs Greater Los Angeles Healthcare System, Los Angeles, California, USA e University Health Network, Toronto, Ontario, Canada f Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada g Department of Medicine, Section of Cardiovascular Medicine, New Haven, Connecticut, USA h Yale University School of Medicine, Center for Outcomes Research and Evaluation, Yale New Haven Hospital, New Haven, Connecticut, USA i Department of Epidemiology and Public Health, Section of Health Policy and Administration, New Haven, Connecticut, USA j Robert Wood Johnson Clinical Scholars Program, New Haven, Connecticut, USA

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The Effect of Education by Pharmacists for Hyperlipidemic Patients Treated With Statins on Patient’s Beliefs About Proper Use of Medications

Introduction: Hyperlipidemia is one of the most common chronic diseases found in millions of people. Studies have shown that the patient’s adherences to medication instructions provided by the pharmacist or doctor are important, yet unfortunately many patients do not adhere to proper usage of these drugs. The aim of this study was the evaluation of the effect of education by pharmacists f...

متن کامل

Cholesterol suppresses antimicrobial effect of statins

Objective(s):Isoprenoid biosynthesis is a key metabolic pathway to produce a wide variety of biomolecules such as cholesterol and carotenoids, which target cell membranes. On the other hand, it has been reported that statins known as inhibitors of isoprenoid biosynthesis and cholesterol lowering agents, may have a direct antimicrobial effect on the some bacteria. The exact action of statins in ...

متن کامل

When choosing statin therapy: the case for generics.

The development of "Top 5" lists across specialties and at regular intervals can help to remind physicians that optimal care is often possible at a lower cost. For purposes of cardiovascular risk reduction, generic statins, or their brand equivalents if priced similarly, remain the appropriate choice for dyslipidemic patients initiating statin therapy. In this article, we review the evidence su...

متن کامل

Statins: Newer Roles Including Lipid Lowering Therapy

Statins are most effective pharmacologically agents to decrease total plasma cholesterol level by competitive inhibition of HMG-Co A reductase. Apart from the well-known LDL and cholesterol lowering effect, statins have been postulated to exert other beneficial effects also called pleotropic or non-lipid effects. Better understanding of various pleotropic effects of statins has prompted a new s...

متن کامل

Development of a Generic Risk Matrix to Manage Project Risks

A generic risk matrix is presented for use identifying and assessing project risks quickly and cost effectively. It assists project managers with few resources to perform project risk analysis. The generic risk matrix (GRM) contains a broad set of risks that are categorized and ranked according to their potential impact and probability of occurrence. The matrix assists PMs in quickly identifyin...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • The Canadian journal of cardiology

دوره 29 4  شماره 

صفحات  -

تاریخ انتشار 2013